Island of Lost Souls (1933)
Now that Criterion has released an incredible version of this on DVD and Blu-ray, everyone should go out and grab it. I hadn't seen this in ages, and the last time was off a crappy VHS. Truly one of the best and most startling horror films of the 30s, with some incredible make-up and a truly disturbing message. Laughton's performance is chilling and unhinged; really, the whole film is that way. Obviously, highly recommended.